Standard BioTools on LinkedIn: #appnote #immuneprofiling #cytometry #cellbiology (2024)

Regular pathogen surveillance is key all year round as a method to help control outbreaks, with epidemiologically significant variants constantly emerging. qPCR is universally used to detect and quantify pathogens, but conventional methods are time consuming and labor-intensive when several pathogens must be detected in a short period, such as when rapid detection of a virus with multiple mutations is required. Take a look through these examples of how the simultaneous detection and quantification of a large number of pathogens using IFCs instead of microtiter plates can reduce cost, time, labor and reagents: https://lnkd.in/gKjBzxYy #wastewater #respiratoryviruses #foodborneillness #antimicrobialresistance

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Thank you to Jolanda Sarno, PhD, Junior Group Leader, Tettamanti Research Center, Fondazione IRCCS San Gerardo dei Tintori, for her excellent talk at the GIC Italian Cytometry Conference this week! She discussed how single-cell classification of B-cell precursor acute lymphoblastic #leukemia by #CyTOF reveals predictors of treatment resistance.We appreciate the interest and questions at the Standard BioTools booth about the ease of analyzing immune cells, intracellular cytokines, intracellular phosphoproteins, transcription factors and cell state simultaneously, and a big thanks to Paolo Santino, Glòria Martrus Zapater, Daniela Natale!

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Don’t miss it! Reserve your seat for this complimentary one-day event, including lunch and evening co*cktail and networking reception: https://lnkd.in/gX-qAvSUCelebrate with us, and take the opportunity to talk with leaders in the fields of immunology, biomedicine, pathology and more… as they discuss how single-cell technologies advance our understanding of disease using immune profiling, tissue mapping, functional analysis, biomarker identification and applied data analysis. See you in San Francisco on June 17!

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We are summer ready at #EACR2024! Stop by Booth 59 to meet the team and discuss how immune, protein and genomic profiling approaches can support discovery through screening…And see technology in action at these poster presentations:Tuesday, June 11 | 11:00 am–6:00 pm→ Poster 1258: Next Generation of #SpatialBiology: High-Throughput Multiplexed Imaging Mass Cytometry™ With Whole Slide Modes→ Poster 1260: Novel Whole Slide #Imaging Modes for Imaging Mass Cytometry Unveil Extensive Cellular Heterogeneity in Human GliomasWednesday, June 12 | 11:00 am–6:00 pm→ Poster 1257: Enabling Fast and Convenient #ImmuneProfiling of Fresh and Long-Term Stabilized Human Whole Blood Samples With CyTOF®→ Poster 1259: Novel Whole Slide Imaging Modes for Imaging Mass Cytometry Reveal Cellular and Structural Composition of Mouse #Glioblastoma

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Complementarity among technologies can expand how we think about research questions. It can broaden our approach and offer more insights from each sample. Hear Jared Burks, PhD, discuss ways in which we can multiplex multiple modalities together. Learn how technologies can work in harmony, pairing suspension and imaging data, to answer larger and more detailed questions.Walk through one of these processes with Burks: https://lnkd.in/gEpEcsNV#multiplexing #cytometry #imaging #innovation

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In a study of mouse embryo normal brain and glioblastoma tissues, a 44-marker neuro-oncology panel composed of the Maxpar OnDemand™ Mouse Immuno-Oncology IMC™ Panel Kit and the Maxpar Neuro Phenotyping IMC Panel Kit revealed the spatial distribution of over 40 distinct molecular markers.A Preview Mode scan using Hyperion XTi™ rapidly identified areas with high tumor and immune cell activity, which was used to identify relevant regions of interest for detailed Cell Mode investigation. Multiplex Cell Mode images using tumor- (top) and immune- (bottom) specific markers demonstrate the heterogeneity of the tumor microenvironment.Get more details on this and other applications for high-plex tissue imaging: https://lnkd.in/gwSDzSaD#lookbook #spatialbiology #neurooncology #tumorcell #immunecell #glioblastoma

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Why not do other things with your day? Hear how the automation built into CyTOF XT™ can change the way you work.Watch this and other thoughts on using CyTOF® technology: https://lnkd.in/gBYfBFzM#cytometry #labautomation

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Antimicrobial resistance is key for newly evolving environmental microbes and human pathogens. We’d like to highlight this new work from the University of Yamanashi that simultaneously quantified antibiotic resistance genes in wastewater using high-throughput qPCR to understand the relationship between #pathogens and #antibioticresistance.Read the #publication to learn how wastewater-based #epidemiology focusing on quantifying pathogens and biological markers present in wastewater is vital to informing #publichealth efforts. Microfluidics-based high-throughput qPCR successfully analyzed pathogens and ARGs in a single run, concurrently assessing 14 distinct assays.Shrestha et al. 2024: https://lnkd.in/gubV6fhZ

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A must-see session highlighting what you could be missing… See results from a direct head-to-head comparison of intracellular target resolution between #CyTOF and fluorescent cytometry. Jennifer Snyder-Cappione, PhD, discusses how CyTOF® flow cytometry can enhance understanding of the dynamics of immune responses and open new avenues for targeted therapies: https://lnkd.in/gZnuNahM#cytokines #phosphorylation #transcriptionfactors#inflammation

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